Space Ghost Coast to Coast is an American animated parody talk show, hosted by Space Ghost. Though the original 1960s series aired as a standard Hanna-Barbera Saturday-morning superhero cartoon, Space Ghost Coast to Coast was a total reboot of the series intended for adults, now reinterpreted as a surreal spoof talk show and produced using the original artwork.
Space Ghost Coast to Coast was recommended to be the first fully produced Cartoon Network original series, and premiered on April 15, 1994. The first two seasons were presented as a serious talk show with subdued jokes, while the later seasons relied more on surrealism, non-sequiturs, and parodies. In 2001, it moved to the network's late night television block Adult Swim.
- George Lowe - Space Ghost, Salesman, and various other characters
- C. Martin Croker - Zorak, Moltar, and various other characters
- Andy Merrill - Brak, Lokar, and various other characters
- Don Kennedy - Tansit
- Judy Tenuta - Black Widow (also appeared as herself, as a guest)
- Scott Finnel - Harvey Birdman
- Dave Willis - various characters
- Brad Abrell - Chad Ghostal
- Bobcat Goldthwait - Himself